Ty (a 50 year old male patient) suffering from pneumonia was given 1000mg IV bolus dose of the antibiotic Z. The following table contains hisTY (a 50-year-old male patient) suffering from pneumonia was given 1000 mg IV bolus dose of the antibiotic Z. The following table contains his plasma concentrations: Time (min) Concentration (mg/L) 5min 7.8mg/L 30min 5.7mg/L 60min 3.9mg/L 100min 2.4mg/L 200min 0.7mg/L 1) Plot the data. (5 marks) 2) Calculate the pharmacokinetic parameters for antibiotic Z in this patient. (5 marks) 3) What can you derive about antibiotic Z from the calculated pharmacokinetic parameters? (5 marks)
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